I've experienced this same problem since 10.04.
My system is built from a DFI LP DK 790FXB-M2RSH motherboard with the ALC889, an AMD Phenom X4 9750 CPU, 4 GBs of RAM and a GeForce GTX 260-192.
I solved the problem by simply revoking the previously applied overclock from my CPU. After doing so, the skipping problems do not occur anymore.
I've experienced this same problem since 10.04.
My system is built from a DFI LP DK 790FXB-M2RSH motherboard with the ALC889, an AMD Phenom X4 9750 CPU, 4 GBs of RAM and a GeForce GTX 260-192.
I solved the problem by simply revoking the previously applied overclock from my CPU. After doing so, the skipping problems do not occur anymore.