Glyph, I don't think the removal of gi.pygtkcompat has happened yet. It's still there with a DeprecationWarning, but for some reason can cause twisted to crash. I haven't investigated the crash into pygobject source myself, but the patch I submitted to upstream twisted will get rid of the warning and the crash, and still work on both the new and old versions of pygobject, as it tries the new API and falls back to the old.
Glyph, I don't think the removal of gi.pygtkcompat has happened yet. It's still there with a DeprecationWarning, but for some reason can cause twisted to crash. I haven't investigated the crash into pygobject source myself, but the patch I submitted to upstream twisted will get rid of the warning and the crash, and still work on both the new and old versions of pygobject, as it tries the new API and falls back to the old.