Comment 2 for bug 1506080

I am having the same issue,

Nothing is written in the ~/.cache/simple-scan/simple-scan.log file.

Running simple-scan -d prints this to shell
[+0.00s] DEBUG: simple-scan.vala:674: Starting Simple Scan 3.18.1, PID=14680
[+0.01s] DEBUG: Connecting to session manager
[+0.07s] DEBUG: ui.vala:2018: Loading state from /home/****/.cache/simple-scan/state
[+0.07s] DEBUG: ui.vala:1986: Restoring window to 600x400 pixels
[+0.07s] DEBUG: autosave-manager.vala:64: Loading autosave information
[+0.07s] DEBUG: autosave-manager.vala:259: Waiting to autosave...
simple-scan: symbol lookup error: /usr/lib/x86_64-linux-gnu/libgusb.so.2: undefined symbol: libusb_has_capability

Nothing in /usr/lib/sane. The directory doesn't even exist.