For what it is worth, there seem to be limitations with the wheel design that might cause a problem for my uses. One is that wheel doesn't attempt to make binaries for linux. Of course, there's a good reason for that, which is that it is impossible to make one that is actually reliable portable to multiple linuxes. But, distutils/setuptools/distribute/new-setuptools/eggs make a half-assed attempt at it, and that might be better for some uses than wheel's principled refusal to try at all.
One doesn't preclude the other.
For what it is worth, there seem to be limitations with the wheel design that might cause a problem for my uses. One is that wheel doesn't attempt to make binaries for linux. Of course, there's a good reason for that, which is that it is impossible to make one that is actually reliable portable to multiple linuxes. But, distutils/ setuptools/ distribute/ new-setuptools/ eggs make a half-assed attempt at it, and that might be better for some uses than wheel's principled refusal to try at all.