Comment 2 for bug 1621121

Hi,
libvirt is build --with-numactl on
  amd64 i386 ia64 mips mipsel powerpc ppc64el s390x

You can check effectively if it was built against it by checking for the lib depend like:
ldd /usr/sbin/libvirtd | grep numa
        libnuma.so.1 => /usr/lib/x86_64-linux-gnu/libnuma.so.1 (0x00007f99e4a39000)

For further debugging until we can reproduce, can you enable more debugging of libvirt and add the more verbose libvirt log here so you and we can check for issues in it?
See:
 http://libvirt.org/guide/html/Application_Development_Guide-Connections-Debug.html