Comment 14 for bug 1572121

I just upgraded to 16.04 and have a lot of files on a ntsf partition that synapse is not able to open. I solved it by adding 'noexec' in the options column of /etc/fstab for that partition.

on a ext4 filesystem if the file has execution permission it will try to execute instead of open
So I guess chmod -x to all your non-executable files should be a workaround